Antidepressants--yes or no?

Genetically Modified Food: Yes or No?

Antidepressants in bipolar depression: yes, no, maybe?

Antidepressants are widely used in the treatment of bipolar depression despite relatively meagre evidence for their efficacy and significant concerns that their prescription can precipitate an acute affective switch into mania/hypomania and that long-term administration can lead to mood instability. Therefore, the use of antidepressants to treat bipolar depression is an important but contentiou...

radical iort, yes or no?

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Pheochromocytoma: yes or no?

A 76-year-old woman was admitted for cardiac decompensation, hypertension, and renal failure. To explore her chronic hypertension, urinary fractionated metanephrines were quantified. Fig. 1A shows the chromatogram of the patient’s urine, and Fig. 1B shows the chromatogram of a calibration standard. A very large methoxytyramine peak was observed (Fig. 1A, black arrow). The peak signal was satura...

Cognitive impairment: yes or no?

value cannot rule out the possibility that some area in the brain may be hypoxic or ischemic. We agree that this is a major limitation of the method. However, the same triticism could be brought against the measurement of cerebral oxygenation by methods that monitor a very limited cerebrd area, such as near-infrared spectroscopy (NIRS) or direct cerebral oxygen measurement with intracerebra1 pr...